New Real-Time PCRs to Differentiate Rickettsia spp. and Rickettsia conorii
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چکیده
منابع مشابه
Fatal Rickettsia conorii subsp. israelensis Infection, Israel
Underdiagnosis of fatal spotted fever may be attributed to nonspecific clinical features and insensitive acute-phase serologic studies. We describe the importance of molecular and immunohistochemical methods in establishing the postmortem diagnosis of locally acquired Israeli spotted fever due to Rickettsia conorii subsp. israelensis in a traveler returning to Israel from India.
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In vitro susceptibilities of Rickettsia rickettsii and Rickettsia conorii to roxithromycin, pristinamycin, and the pristinamycin compounds, P1 and P2, were determined by a dye uptake assay and a plaque assay. The MICs were 1 microgram/ml for roxithromycin, 2 micrograms/ml for pristinamycin, greater than 256 micrograms/ml for P1, and 2 micrograms/ml for P2. Compounds P1 and P2 did not share syne...
متن کاملSmall Regulatory RNAs of Rickettsia conorii
Small regulatory RNAs comprise critically important modulators of gene expression in bacteria, yet very little is known about their prevalence and functions in Rickettsia species. R. conorii, the causative agent of Mediterranean spotted fever, is a tick-borne pathogen that primarily infects microvascular endothelium in humans. We have determined the transcriptional landscape of R. conorii durin...
متن کاملFamily outbreak of Rickettsia conorii infection.
3. Santos MR, Ghandi S, Vogler M, Hanna BA, Holzman RS. Suspected diphtheria in a Uzbek national; isolation of C. pseudodiphtheriticum resulted in a false positive presumptive diagnosis. Clin Infect Dis 1996;22:735. 4. Izurieta HS, Strebel PM, Youngblood T, Hollis DG, Popovic T. Exudative pharyngitidis possibly due to C. pseudodiphtheriticum, a new challenge in the differential diagnosis of dip...
متن کاملRickettsia conorii Transcriptional Response within Inoculation Eschar
BACKGROUND Rickettsia conorii, the causative agent of the Mediterranean spotted fever, is transmitted to humans by the bite of infected ticks Rhipicephalus sanguineus. The skin thus constitutes an important barrier for the entry and propagation of R. conorii. Given this, analysis of the survival strategies used by the bacterium within infected skin is critical for our understanding of rickettsi...
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ژورنال
عنوان ژورنال: Molecules
سال: 2020
ISSN: 1420-3049
DOI: 10.3390/molecules25194431